Showing posts with label metabolism. Show all posts
Showing posts with label metabolism. Show all posts

Tuesday, 6 September 2016

Keeping the Weight Off

Weight loss and maintenance of weight loss is difficult if not nearly impossible for most people.

A registry of individuals who have lost 30 pounds or more and maintained their weight loss over a year exists in the U.S. This research effort is known as the National Weight Control Registry. It currently has over 10,000.

I was looking at some of the published research results from this study. A paper published in 2012 used cluster analysis to identify sub-types of individuals with successful long-term weight loss.

The study identified four specific sub-types of successful dieters. The varied on a variety of historical, demographic and behavioral variables. However, I was impressed by the amount of exercise the participants documented.

Over 90% of the successful dieters burned an average of 2500 calories in a typical week of physical activity. Although calories burned by exercise varies by weight a typical weekly amount of exercise to burn 2500 calories per week would be:

  • Walking 25 miles per week (six plus hours walking per week)
  • Running 18 miles per week (three plus hours running per week)

These levels of physical activity are two to three times more than typical recommendations for physical activity in the general population.

This study suggests successful weight loss maintenance is hard work. Unless you are committed to and capable of this level of activity it may be nearly impossible to lose weight and keep the weight off.

Readers with more interest in this study can access the free full-text manuscript by clicking on the PMID link in the citation below.

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Photo of fireworks is a Moto G4 plus smartphone pic from my files.

Ogden, L., Stroebele, N., Wyatt, H., Catenacci, V., Peters, J., Stuht, J., Wing, R., & Hill, J. (2012). Cluster Analysis of the National Weight Control Registry to Identify Distinct Subgroups Maintaining Successful Weight Loss Obesity, 20 (10), 2039-2047 DOI: 10.1038/oby.2012.79

Tuesday, 3 May 2016

"The Biggest Loser": Long-term Effects

Yesterday I posted a link to a New York Times article that posted a summary outcome in fourteen participants in TV's "The Biggest Loser" show.

The study found a trend towards post-show weight gain for 13/14 of the participants.

Four participants actually gained so much weight that after six years they weighed more than before participating in the show.

A key finding from the study was this weight gain could be explained by a metabolic response resulting in up to 800 calories less burned daily after weight loss.

I have previously posted notes from a lecture I attended by Dr. Kevin Hall who is mentioned in the NYT piece.

For me, the take home message is that long-term weight loss maintenance is extremely difficult. A better strategy might be to aim for consuming a healthy diet and achieving daily recommended exercise levels.

A link to the NYT article is here:

Notes on Dr. Hall's lecture at the Laureate Institute for Brain Research is here:

Follow me on Twitter: @WRY999

Graphic is an original screen shot from my Twitter feed.

Fothergill, E., Guo, J., Howard, L., Kerns, J., Knuth, N., Brychta, R., Chen, K., Skarulis, M., Walter, M., Walter, P., & Hall, K. (2016). Persistent metabolic adaptation 6 years after “The Biggest Loser” competition Obesity DOI: 10.1002/oby.21538

Thursday, 4 November 2010

The Future of Diabetes

Diabetes is a disease in which the body either does not produce enough insulin or does not effectively use the insulin it produces. People with diabetes often take insulin, a hormone that converts food into energy, to control high blood sugar. As the fastest growing disease in the United States, someone develops diabetes every 20 seconds. In the Philadelphia region the risk of having diabetes is even greater than in other major cities.


In honor of American Diabetes Month, the Penn Medicine Institute for Diabetes, Obesity & Metabolism is proud to host the educational event, The Future of Diabetes: Reversing Trends, Promoting Health and Finding a Cure on Thursday, November 11. At the event, a panel of Penn Medicine experts and Philadelphia city officials discuss the current state of diabetes care and what the future holds for diabetes treatment.